Q-omics provides the consensus-scored DEFB108C profile across patient tissues and cancer cell-line models. DEFB108C expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, DEFB108C RNA expression shows 5,038 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where DEFB108C shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB108C survival associations across molecular data types. DEFB108C RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB108C data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	KIRC (78)	view →

This table ranks reproducible DEFB108C RNA expression–survival associations across cancer types. High DEFB108C expression shows unfavorable associations in KIRC, ESCA and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for DEFB108C RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.142	0.659	<.001	78	view →
ESCA	OS	Tertile	II,III,IV	0.136	0.703	<.001	72	view →
SKCM	DFS	Tertile	All	0.023	0.738	<.001	18	view →

Pink = unfavorable, green = favorable. all 3 lineages →

DEFB108C-KIRC (OS)

Kaplan–Meier survival curve for DEFB108C RNA expression in KIRC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB108C in patient tissues and cancer cell lines. In patient samples, DEFB108C shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,038	STAD (4997)	view →
RNA	3,844	LUSC (1860)	view →