Across TCGA patient cohorts, DEFB108B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,515 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DEFB108B-associated proteins across cancer lineages are IMPDH1, NUMA1, and PDS5B. Each is linked with DEFB108B in more than 4 cancer types. Because this analysis shows association rather than direction, both DEFB108B-to-partner and partner-to-DEFB108B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB108B→partner) and Y-score (partner→DEFB108B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMPDH1 →	-0.422	-0.665	<.001	<.001	3	4
HNSC	NUMA1 →	+0.617	+0.815	<.001	<.001	2	5
UCEC	PDS5B →	+0.306	+0.647	<.001	<.001	3	4
CCRCC	TBC1D2 →	-0.348	-0.399	.007	.005	3	4
GBM	ACIN1 →	+0.252	+0.511	.001	<.001	3	4
GBM	HNRNPK →	+0.253	+0.541	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,515 associations by consensus.

Exploration

DEFB108B survival (RNA) · tumor vs normal (RNA) · all DEFB108B data types