Across TCGA cell cohorts, DEFB108B RNA expression is significantly associated with the mutation status of many other genes, with 294 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEFB108B-associated genes across cancer lineages are ATP8B2, MED12, and SNAPC4. Each is linked with DEFB108B in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB108B-to-partner and partner-to-DEFB108B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB108B→partner) and Y-score (partner→DEFB108B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ATP8B2 →	+5.169	+0.046	.004	<.001	3	2
BONE	MED12 →	+4.169	+0.035	.008	<.001	3	2
KIDNEY	SNAPC4 →	+5.000	+0.080	.005	<.001	3	2
BLOOD_Leukemia	MYBBP1A →	+2.514	+0.051	.005	.009	3	2
BLOOD_Lymphoma	NTRK2 →	+4.000	+0.075	<.001	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	SDK2 →	+4.736	+0.194	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 294 associations by consensus.

Exploration

DEFB108B survival (RNA) · tumor vs normal (RNA) · all DEFB108B data types