DEFB108A

Across TCGA patient cohorts, DEFB108A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,324 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB108A-associated GO terms across cancer lineages are Regulation of carbohydrate metabolic process, Neuron migration, and Regulation of lipid localization. Each is linked with DEFB108A in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB108A-to-partner and partner-to-DEFB108A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of carbohydrate metabolic process grouped by DEFB108A-low versus DEFB108A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB108A→partner) and Y-score (partner→DEFB108A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of carbohydrate metabolic process →	+0.076	+0.073	<.001	<.001	3	3
STAD	Neuron migration →	+0.051	+0.085	<.001	<.001	3	2
STAD	Regulation of lipid localization →	+0.064	+0.067	<.001	<.001	3	2
STAD	Negative regulation of myeloid leukocyte differentiation →	+0.063	+0.064	<.001	<.001	3	2
STAD	DNA damage response, signal transduction by p53 class mediator →	+0.096	+0.074	<.001	<.001	3	2
STAD	Positive regulation of transmembrane transport →	+0.049	+0.076	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,324 associations by consensus.

Regulation of carbohydrate metabolic process by DEFB108A expression — STAD

Explore this box plot interactively →