Q-omics provides the consensus-scored DEFB108A profile across patient tissues and cancer cell-line models. DEFB108A expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in THYM. Additionally, DEFB108A RNA expression shows 5,852 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight THYM, and LUSC as cancer lineages where DEFB108A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB108A survival associations across molecular data types. DEFB108A RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB108A data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	THYM (72)	view →

This table ranks reproducible DEFB108A RNA expression–survival associations across cancer types. High DEFB108A expression shows unfavorable associations in THYM, UCEC, LIHC, STAD, TGCT and KIRC. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for DEFB108A RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.068	0.977	<.001	72	view →
UCEC	OS	Tertile	All	0.103	0.678	.004	36	view →
LIHC	OS	Tertile	All	0.061	0.783	<.001	36	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
TGCT	DFS	Tertile	All	0.059	0.802	<.001	18	view →
KIRC	DFS	Tertile	IV	0.039	0.632	<.001	18	view →

Pink = unfavorable, green = favorable. all 6 lineages →

DEFB108A-THYM (OS)

Kaplan–Meier survival curve for DEFB108A RNA expression in THYM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB108A in patient tissues and cancer cell lines. In patient samples, DEFB108A shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,852	LUSC (4547)	view →
Function (RNA)	5,324	STAD (5316)	view →