DEFB103B

Across TCGA patient cohorts, DEFB103B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,721 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DEFB103B-associated GO terms across cancer lineages are ERBB2-EGFR signaling pathway, Positive regulation of skeletal muscle tissue regeneration, and Regulation of skeletal muscle tissue regeneration. Each is linked with DEFB103B in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB103B-to-partner and partner-to-DEFB103B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB2-EGFR signaling pathway grouped by DEFB103B-low versus DEFB103B-high in CESC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB103B→partner) and Y-score (partner→DEFB103B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ERBB2-EGFR signaling pathway →	+0.097	+0.010	<.001	.002	3	3
ESCA	Positive regulation of skeletal muscle tissue regeneration →	+0.159	+0.448	<.001	<.001	3	3
ESCA	Regulation of skeletal muscle tissue regeneration →	+0.183	+0.456	<.001	<.001	3	3
ESCA	Regulation of epidermis development →	+0.045	+0.517	<.001	<.001	3	3
ESCA	Response to fungus →	+0.045	+0.440	<.001	<.001	3	3
ESCA	Epidermal cell differentiation →	+0.052	+0.437	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,721 associations by consensus.

ERBB2-EGFR signaling pathway by DEFB103B expression — CESC

Explore this box plot interactively →