DECR2

Across TCGA patient cohorts, DECR2 mutation is significantly associated with the RNA expression of many other genes, with 165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DECR2-associated genes across cancer lineages are BCRP6, RN7SKP250, and RNU6-1140P. Each is linked with DECR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DECR2-to-partner and partner-to-DECR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCRP6 grouped by DECR2-low versus DECR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DECR2→partner) and Y-score (partner→DECR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BCRP6 →	+0.104	+4.686	<.001	<.001	3	1
LUSC	RN7SKP250 →	+0.155	+7.327	<.001	<.001	3	1
LUSC	RNU6-1140P →	+0.592	+5.625	<.001	.004	3	1
LUSC	H2BP7 →	+0.137	+6.438	<.001	.001	3	1
LUSC	RNU6-277P →	+0.417	+5.093	<.001	.008	3	1
LUSC	RNU6-111P →	+0.455	+7.102	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 165 associations by consensus.

BCRP6 by DECR2 expression — COAD

Explore this box plot interactively →