DEAF1

Across TCGA patient cohorts, DEAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,796 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DEAF1-associated genes across cancer lineages are ATG16L2, PHYHD1, and IGHV1OR16-3. Each is linked with DEAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEAF1-to-partner and partner-to-DEAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEAF1 versus ATG16L2 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEAF1→partner) and Y-score (partner→DEAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATG16L2 →	+0.863	+0.378	.004	.001	3	2
BRCA	PHYHD1 →	+1.307	+0.292	<.001	.003	3	2
LUAD	IGHV1OR16-3 →	+0.929	+0.226	.001	.003	3	2
PDAC	MRPS10 →	-0.742	-0.431	<.001	.001	3	2
OV	MIR210HG →	-0.853	-0.567	.005	.005	3	2
BRCA	PIK3IP1 →	+0.848	+0.440	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,796 associations by consensus.

DEAF1 vs ATG16L2 — BRCA

Explore this scatter interactively →