DDX60

Across TCGA cell cohorts, DDX60 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,246 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX60-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Positive regulation of protein binding, and Negative regulation of viral genome replication. Each is linked with DDX60 in more than 17 cancer types. Because this analysis shows association rather than direction, both DDX60-to-partner and partner-to-DDX60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by DDX60-low versus DDX60-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX60→partner) and Y-score (partner→DDX60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Cytoplasmic pattern recognition receptor signaling pathway →	+0.100	+1.866	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Positive regulation of protein binding →	+0.153	+2.007	<.001	.003	3	17
LUNG_NSCLC_LUSC	Negative regulation of viral genome replication →	+0.244	+2.321	.001	.005	3	17
KIDNEY	Defense response to virus →	+0.104	+1.826	.001	<.001	3	17
LUNG_NSCLC_LUSC	Pattern recognition receptor signaling pathway →	+0.081	+1.908	<.001	.001	3	17
LUNG_NSCLC_LUSC	Activation of innate immune response →	+0.081	+2.278	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,246 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by DDX60 expression — BLOOD_Lymphoma

Explore this box plot interactively →