DDX6

Across TCGA patient cohorts, DDX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,106 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDX6-associated proteins across cancer lineages are GATAD2B, RPRD2, and LSM14B. Each is linked with DDX6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DDX6-to-partner and partner-to-DDX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX6 versus GATAD2B in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX6→partner) and Y-score (partner→DDX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GATAD2B →	+0.294	+0.299	<.001	<.001	3	5
LUAD	RPRD2 →	+0.253	+0.297	<.001	<.001	3	5
LSCC	LSM14B →	+0.486	+0.384	<.001	<.001	3	5
UCEC	POGZ →	+0.214	+0.214	<.001	<.001	3	5
GBM	PTPRC →	-0.854	-0.461	<.001	<.001	3	5
GBM	YTHDC1 →	+0.268	+0.258	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,106 associations by consensus.

DDX6 vs GATAD2B — GBM

Explore this scatter interactively →