DDX6

Across TCGA cell cohorts, DDX6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,332 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX6-associated GO terms across cancer lineages are Ether catabolic process, Glycerol ether catabolic process, and Platelet activating factor catabolic process. Each is linked with DDX6 in more than 13 cancer types. Because this analysis shows association rather than direction, both DDX6-to-partner and partner-to-DDX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ether catabolic process grouped by DDX6-low versus DDX6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX6→partner) and Y-score (partner→DDX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Ether catabolic process →	+0.203	+0.810	<.001	<.001	3	14
OVARY	Glycerol ether catabolic process →	+0.203	+0.810	<.001	<.001	3	14
OVARY	Platelet activating factor catabolic process →	+0.203	+0.810	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.129	+0.987	<.001	<.001	3	14
SOFT_TISSUE	Regulation of chromosome segregation →	+0.093	+0.658	.008	.007	3	14
SOFT_TISSUE	Regulation of chromosome organization →	+0.068	+0.728	.005	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,332 associations by consensus.

Ether catabolic process by DDX6 expression — OVARY

Explore this box plot interactively →