DDX55

Across TCGA pan-cancer cohorts, DDX55 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDX55 data layer compared with 27 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher DDX55 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DDX55 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

READ, UCEC, and HNSC are the cancer types where DDX55 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.111	0.919	<.001	42	view →
UCEC	DFS	Median	All	1.000	0.618	.004	32	view →
HNSC	OS	Median	All	0.282	0.663	.006	24	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DDX55–READ (OS)

Open the READ breakdown →