DDX55

Across TCGA pan-cancer cohorts, DDX55 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DDX55’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DDX55 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX55 is over-expressed in tumor.

HNSC, COAD, and BLCA are the cancer types where DDX55 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX55 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+1.029	<.001	12	view →
COAD	Female	II,III,IV	+1.214	<.001	11	view →
BLCA	Male	All	+0.958	<.001	11	view →
KIRC	Male	IV	+0.891	<.001	11	view →
KIRP	All	III,IV	+0.761	<.001	11	view →
STAD	Male	II,III,IV	+1.111	<.001	9	view →
LIHC	Female	III,IV	+1.045	<.001	9	view →
LUAD	Male	III,IV	+0.813	<.001	9	view →
LUSC	Male	III,IV	+1.169	<.001	8	view →
READ	Female	All	+1.284	<.001	7	view →
BRCA	All	II,III,IV	+0.290	<.001	6	view →
CHOL	Male	All	+1.898	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DDX55–HNSC

Open the HNSC breakdown →