DDX55

Across TCGA patient cohorts, DDX55 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX55-associated genes across cancer lineages are ASNS, FOXO3a, and Akt_pT308. Each is linked with DDX55 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX55-to-partner and partner-to-DDX55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by DDX55-low versus DDX55-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX55→partner) and Y-score (partner→DDX55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.479	+2.415	<.001	.003	3	3
UCEC	FOXO3a →	+0.087	+1.375	.015	.024	3	2
UCEC	Akt_pT308 →	+0.461	+2.000	.038	.029	3	2
UCEC	c-Met_pY1235 →	+0.059	+1.331	.024	.043	3	2
COAD	EGFR_pY1068 →	-0.506	-2.991	.002	.036	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.433	+1.817	.016	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by DDX55 expression — UCEC

Explore this box plot interactively →