DDX55

Across TCGA cell cohorts, DDX55 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,976 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DDX55-associated GO terms across cancer lineages are Double-strand break repair, Recombinational repair, and DNA damage checkpoint signaling. Each is linked with DDX55 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX55-to-partner and partner-to-DDX55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by DDX55-low versus DDX55-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX55→partner) and Y-score (partner→DDX55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Double-strand break repair →	+0.085	+1.151	.007	<.001	3	19
SOFT_TISSUE	Recombinational repair →	+0.076	+0.821	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.087	+1.150	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA integrity checkpoint signaling →	+0.095	+0.779	<.001	.005	3	19
BONE	DNA replication →	+0.091	+0.696	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Mitotic cell cycle checkpoint signaling →	+0.109	+1.113	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,976 associations by consensus.

Double-strand break repair by DDX55 expression — BONE

Explore this box plot interactively →