DDX54

Across TCGA cell cohorts, DDX54 mutation is significantly associated with the RNA expression of many other genes, with 508 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX54-associated genes across cancer lineages are RASAL1, LRIT1, and GMCL2. Each is linked with DDX54 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX54-to-partner and partner-to-DDX54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RASAL1 grouped by DDX54-low versus DDX54-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX54→partner) and Y-score (partner→DDX54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RASAL1 →	+1.403	+3.489	.005	.001	3	3
UPPER_AERODIGESTIVE_TRACT	LRIT1 →	+0.028	+3.285	.004	.006	3	3
LARGE_INTESTINE	GMCL2 →	+0.037	+3.691	.002	.002	3	3
BLOOD_Leukemia	CNGA2 →	+0.025	+2.954	.004	.005	3	2
BLOOD_Leukemia	PRR30 →	+0.009	+2.684	<.001	.004	3	2
BLOOD_Leukemia	SBK1 →	+1.830	+3.214	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 508 associations by consensus.

RASAL1 by DDX54 expression — BLOOD_Leukemia

Explore this box plot interactively →