Across TCGA patient cohorts, DDX53 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,209 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DDX53-associated GO terms across cancer lineages are Intracellular protein transmembrane transport, Telomere organization, and Positive regulation of DNA metabolic process. Each is linked with DDX53 in more than 12 cancer types. Because this analysis shows association rather than direction, both DDX53-to-partner and partner-to-DDX53 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX53→partner) and Y-score (partner→DDX53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Intracellular protein transmembrane transport →	+0.089	+0.255	<.001	.001	3	13
ESCA	Telomere organization →	+0.073	+0.456	<.001	<.001	3	13
STAD	Positive regulation of DNA metabolic process →	+0.063	+0.186	<.001	<.001	3	13
ESCA	Protein-DNA complex assembly →	+0.063	+0.314	<.001	.002	3	12
STAD	Mitotic DNA integrity checkpoint signaling →	+0.062	+0.192	<.001	<.001	3	12
STAD	DNA-templated DNA replication →	+0.062	+0.202	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,209 associations by consensus.

Exploration

DDX53 survival (RNA) · tumor vs normal (RNA) · all DDX53 data types