DDX52

Across TCGA patient cohorts, DDX52 mutation is significantly associated with the RNA expression of many other genes, with 3,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX52-associated genes across cancer lineages are VN1R90P, SPRING1P1, and TLE6. Each is linked with DDX52 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX52-to-partner and partner-to-DDX52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R90P grouped by DDX52-low versus DDX52-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX52→partner) and Y-score (partner→DDX52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VN1R90P →	+0.147	+3.408	.001	.009	3	2
HNSC	SPRING1P1 →	+0.148	+7.132	<.001	<.001	3	2
UCEC	TLE6 →	+0.725	+2.343	.004	.003	3	2
UCEC	GNRH2 →	+0.585	+3.584	<.001	.002	3	2
UCEC	RNU6-1155P →	+0.093	+4.060	.009	.006	3	2
UCEC	LINC01871 →	+0.903	+3.601	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

VN1R90P by DDX52 expression — COAD

Explore this box plot interactively →