Across TCGA patient cohorts, DDX51 mutation is significantly associated with the RNA expression of many other genes, with 874 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX51-associated genes across cancer lineages are RNA5SP87, RNY4P16, and ATXN1L. Each is linked with DDX51 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX51-to-partner and partner-to-DDX51 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX51→partner) and Y-score (partner→DDX51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA5SP87 →	+0.379	+5.450	<.001	.004	3	2
UCEC	RNY4P16 →	+0.143	+3.069	<.001	.005	3	2
UCEC	ATXN1L →	+0.474	+2.850	.003	.001	3	2
UCEC	IGHV3-72 →	+1.063	+2.914	.005	.001	3	2
UCEC	KCNIP2-AS1 →	+0.245	+3.914	.005	<.001	3	2
SKCM	MIR4719 →	+0.246	+4.900	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 874 associations by consensus.

Exploration

DDX51 survival (RNA) · tumor vs normal (RNA) · all DDX51 data types