Across TCGA patient cohorts, DDX51 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX51-associated genes across cancer lineages are p27_pT198, Caspase-7-cleavedD198, and Caspase-8. Each is linked with DDX51 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX51-to-partner and partner-to-DDX51 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX51→partner) and Y-score (partner→DDX51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.114	+2.502	.006	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.772	+3.479	<.001	.002	3	2
UCEC	Caspase-8 →	-0.231	-3.432	.019	.005	3	2
UCEC	Fibronectin →	-0.304	-2.000	.019	.010	3	1
UCEC	p62 Lck ligand →	+0.256	+3.321	.045	.009	3	1
UCEC	p90 RSK →	+0.200	+1.598	.007	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

DDX51 survival (RNA) · tumor vs normal (RNA) · all DDX51 data types