DDX5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDX5 protein abundance is significantly associated with the RNA expression of many other genes, with 18,747 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX5-associated genes across cancer lineages are CENPO, SGO1, and TACO1. Each is linked with DDX5 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDX5-to-partner and partner-to-DDX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX5 versus CENPO in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX5→partner) and Y-score (partner→DDX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCENPO →+0.647+0.278<.001<.00139
UCECSGO1 →+1.043+0.252<.001<.00139
UCECTACO1 →+0.985+0.229<.001<.00139
HNSCCKAP2L →+0.858+0.168<.001.00139
HNSCKPNA2 →+1.091+0.240<.001<.00139
UCECALYREF →+1.154+0.202.003.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,747 associations by consensus.

DDX5 vs CENPO — OV

Per-sample scatter of DDX5 vs CENPO in OV (Pearson r = 0.39).

Explore this scatter interactively →

Exploration