DDX5

Across TCGA cell cohorts, DDX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,240 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX5-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Positive regulation of mRNA metabolic process, and Regulation of termination of RNA polymerase II transcription. Each is linked with DDX5 in more than 15 cancer types. Because this analysis shows association rather than direction, both DDX5-to-partner and partner-to-DDX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by DDX5-low versus DDX5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX5→partner) and Y-score (partner→DDX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.059	+0.777	.002	.001	3	16
STOMACH	Positive regulation of mRNA metabolic process →	+0.077	+0.764	<.001	<.001	3	14
SOFT_TISSUE	Regulation of termination of RNA polymerase II transcription →	+0.101	+0.654	.004	.003	3	14
SOFT_TISSUE	Regulation of termination of DNA-templated transcription →	+0.101	+0.654	.004	.003	3	14
STOMACH	Heterochromatin organization →	+0.079	+0.691	<.001	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.070	+0.755	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

Positive regulation of organelle assembly by DDX5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →