DDX46

Across TCGA cell cohorts, DDX46 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,417 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX46-associated GO terms across cancer lineages are Mitotic nuclear division, DNA strand elongation, and Microtubule organizing center organization. Each is linked with DDX46 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX46-to-partner and partner-to-DDX46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by DDX46-low versus DDX46-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX46→partner) and Y-score (partner→DDX46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Mitotic nuclear division →	+0.109	+1.112	<.001	<.001	3	19
SOFT_TISSUE	DNA strand elongation →	+0.151	+1.001	<.001	<.001	3	19
PANCREAS	Microtubule organizing center organization →	+0.082	+1.051	<.001	<.001	3	19
BLOOD_Myeloma	Nuclear transport →	+0.070	+0.777	<.001	<.001	3	19
BONE	DNA replication →	+0.100	+0.928	.006	<.001	3	19
BONE	DNA-templated DNA replication →	+0.141	+1.035	.007	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,417 associations by consensus.

Mitotic nuclear division by DDX46 expression — SKIN

Explore this box plot interactively →