DDX3Y

Across TCGA patient cohorts, DDX3Y protein abundance is significantly associated with the RNA expression of many other genes, with 3,286 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DDX3Y-associated genes across cancer lineages are USP9Y, KDM5D, and RPS4Y1. Each is linked with DDX3Y in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX3Y-to-partner and partner-to-DDX3Y results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX3Y versus USP9Y in GBM, with a Pearson correlation of 0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX3Y→partner) and Y-score (partner→DDX3Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	USP9Y →	+4.160	+2.406	<.001	<.001	3	7
GBM	KDM5D →	+4.925	+2.406	<.001	<.001	3	7
COAD	RPS4Y1 →	+7.118	+2.024	<.001	<.001	3	7
PDAC	TXLNGY →	+4.098	+2.708	<.001	<.001	3	7
COAD	TMSB4Y →	+2.362	+2.176	<.001	<.001	3	7
GBM	NLGN4Y →	+4.189	+2.406	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,286 associations by consensus.

DDX3Y vs USP9Y — GBM

Explore this scatter interactively →