DDX31

Across TCGA patient cohorts, DDX31 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,192 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX31-associated proteins across cancer lineages are FUBP3, GTF3C4, and EHMT1. Each is linked with DDX31 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX31-to-partner and partner-to-DDX31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX31 versus FUBP3 in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX31→partner) and Y-score (partner→DDX31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FUBP3 →	+0.226	+0.679	<.001	<.001	3	8
LSCC	GTF3C4 →	+0.454	+0.639	<.001	<.001	3	8
GBM	EHMT1 →	+0.460	+0.508	<.001	<.001	3	8
LSCC	SPOUT1 →	+0.429	+0.543	<.001	<.001	3	7
HNSC	WDR5 →	+0.330	+0.807	<.001	<.001	3	7
GBM	SET →	+0.389	+0.417	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,192 associations by consensus.

DDX31 vs FUBP3 — LSCC

Explore this scatter interactively →