DDX28

Across TCGA patient cohorts, DDX28 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,462 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX28-associated proteins across cancer lineages are WWP2, CIAPIN1, and DHX38. Each is linked with DDX28 in more than 6 cancer types. Because this analysis shows association rather than direction, both DDX28-to-partner and partner-to-DDX28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX28 versus WWP2 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX28→partner) and Y-score (partner→DDX28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WWP2 →	+0.347	+0.519	<.001	<.001	3	7
OV	CIAPIN1 →	+0.391	+0.479	<.001	.004	3	6
OV	DHX38 →	+0.218	+0.466	<.001	<.001	3	6
OV	USP10 →	+0.372	+0.534	<.001	<.001	3	5
LSCC	DNAJA2 →	+0.272	+0.565	<.001	<.001	3	5
LSCC	CLUH →	+0.289	+0.381	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,462 associations by consensus.

DDX28 vs WWP2 — LSCC

Explore this scatter interactively →