DDX27

Across TCGA patient cohorts, DDX27 protein abundance is significantly associated with the RNA expression of many other genes, with 22,318 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX27-associated genes across cancer lineages are MYBL2, ZFAS1, and TPX2. Each is linked with DDX27 in more than 8 cancer types. Because this analysis shows association rather than direction, both DDX27-to-partner and partner-to-DDX27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX27 versus MYBL2 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX27→partner) and Y-score (partner→DDX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYBL2 →	+1.386	+0.453	<.001	<.001	3	9
LSCC	ZFAS1 →	+0.651	+0.593	<.001	<.001	3	9
CCRCC	TPX2 →	+1.096	+0.246	<.001	<.001	3	9
OV	CNRIP1 →	-0.669	-0.354	.002	<.001	3	8
LSCC	DKC1 →	+0.814	+0.505	<.001	<.001	3	8
BRCA	ABCA8 →	-1.094	-0.392	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,318 associations by consensus.

DDX27 vs MYBL2 — BRCA

Explore this scatter interactively →