DDX27

Across TCGA cell cohorts, DDX27 mutation is significantly associated with the RNA expression of many other genes, with 1,490 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX27-associated genes across cancer lineages are OR4F15, C10orf62, and OR1L3. Each is linked with DDX27 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX27-to-partner and partner-to-DDX27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F15 grouped by DDX27-low versus DDX27-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX27→partner) and Y-score (partner→DDX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR4F15 →	+0.091	+3.047	<.001	.002	3	2
URINARY_TRACT	C10orf62 →	+0.131	+3.974	.002	<.001	3	2
OVARY	OR1L3 →	+0.023	+2.859	.008	.008	3	2
OVARY	MRGPRG →	+0.090	+3.280	.001	.002	3	2
OVARY	NPSR1 →	+0.037	+4.357	<.001	<.001	3	2
LARGE_INTESTINE	DDHD1 →	+0.842	+3.743	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,490 associations by consensus.

OR4F15 by DDX27 expression — URINARY_TRACT

Explore this box plot interactively →