DDX25

Across TCGA cell cohorts, DDX25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,562 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DDX25-associated GO terms across cancer lineages are Positive regulation of DNA repair, Cell-substrate adhesion, and Epigenetic regulation of gene expression. Each is linked with DDX25 in more than 10 cancer types. Because this analysis shows association rather than direction, both DDX25-to-partner and partner-to-DDX25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by DDX25-low versus DDX25-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX25→partner) and Y-score (partner→DDX25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.076	+1.482	<.001	<.001	3	11
BONE	Cell-substrate adhesion →	-0.144	-1.348	<.001	<.001	3	9
OVARY	Epigenetic regulation of gene expression →	+0.061	+0.746	.001	.004	3	9
BONE	Positive regulation of double-strand break repair →	+0.090	+1.133	<.001	.004	2	10
BONE	Morphogenesis of a branching structure →	-0.073	-1.214	.001	<.001	3	8
BONE	Cell-matrix adhesion →	-0.151	-1.380	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,562 associations by consensus.

Positive regulation of DNA repair by DDX25 expression — BONE

Explore this box plot interactively →