DDX24

Across TCGA cell cohorts, DDX24 mutation is significantly associated with the RNA expression of many other genes, with 392 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX24-associated genes across cancer lineages are GLIPR2, OXNAD1, and TATDN2. Each is linked with DDX24 in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX24-to-partner and partner-to-DDX24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLIPR2 grouped by DDX24-low versus DDX24-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX24→partner) and Y-score (partner→DDX24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GLIPR2 →	+1.233	+3.212	<.001	.006	3	2
LARGE_INTESTINE	OXNAD1 →	+0.518	+3.212	.001	.006	3	2
LARGE_INTESTINE	TATDN2 →	+0.536	+3.212	.003	.006	3	2
LARGE_INTESTINE	TMEM183A →	+0.535	+3.212	.002	.006	3	2
LARGE_INTESTINE	CNOT10 →	+0.531	+3.212	<.001	.006	3	2
LARGE_INTESTINE	CBY1 →	+0.649	+3.299	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 392 associations by consensus.

GLIPR2 by DDX24 expression — LARGE_INTESTINE

Explore this box plot interactively →