DDX23

Across TCGA patient cohorts, DDX23 protein abundance is significantly associated with the RNA expression of many other genes, with 18,245 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDX23-associated genes across cancer lineages are ZNF740, CLEC1A, and LETMD1. Each is linked with DDX23 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX23-to-partner and partner-to-DDX23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDX23 versus ZNF740 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX23→partner) and Y-score (partner→DDX23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF740 →	+0.447	+0.286	<.001	<.001	3	8
BRCA	CLEC1A →	-0.540	-0.238	<.001	<.001	3	7
LSCC	LETMD1 →	+0.378	+0.268	<.001	<.001	3	7
LSCC	SENP1 →	+0.564	+0.306	<.001	<.001	3	7
LSCC	PRIM1 →	+0.738	+0.297	<.001	<.001	3	7
LSCC	TMEM97 →	+1.030	+0.247	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,245 associations by consensus.

DDX23 vs ZNF740 — LSCC

Explore this scatter interactively →