DDX23

Across TCGA cell cohorts, DDX23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,953 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDX23-associated GO terms across cancer lineages are Oocyte growth, DNA strand elongation involved in DNA replication, and Regulation of DNA repair. Each is linked with DDX23 in more than 17 cancer types. Because this analysis shows association rather than direction, both DDX23-to-partner and partner-to-DDX23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by DDX23-low versus DDX23-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX23→partner) and Y-score (partner→DDX23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Oocyte growth →	+0.265	+1.054	<.001	.001	3	18
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.195	+1.059	<.001	<.001	3	17
BONE	Regulation of DNA repair →	+0.064	+0.832	<.001	<.001	3	17
BONE	Double-strand break repair via homologous recombination →	+0.118	+1.228	<.001	<.001	3	17
BREAST	Regulation of chromatin organization →	+0.098	+0.988	<.001	<.001	3	17
BONE	Nucleic acid transport →	+0.127	+0.860	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,953 associations by consensus.

Oocyte growth by DDX23 expression — BONE

Explore this box plot interactively →