DDX20

Across TCGA pan-cancer cohorts, DDX20 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DDX20 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DDX20 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DDX20 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where DDX20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.384	1.000	.001	19	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	9	view →
UCEC	DFS	Tertile	III,IV	1.000	0.383	.020	8	view →
GBM	DFS	Quartile	All	0.461	0.199	.015	4	view →
HNSC	DFS	Median	III,IV	0.726	0.845	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DDX20–CCRCC (DFS)

Open the CCRCC breakdown →