DDX20

Across TCGA patient cohorts, DDX20 mutation is significantly associated with the RNA expression of many other genes, with 4,152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX20-associated genes across cancer lineages are NCAPG, PSMC3IP, and CDCA5. Each is linked with DDX20 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDX20-to-partner and partner-to-DDX20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPG grouped by DDX20-low versus DDX20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX20→partner) and Y-score (partner→DDX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPG →	+0.779	+2.595	<.001	<.001	3	3
UCEC	PSMC3IP →	+0.631	+1.818	<.001	<.001	3	3
UCEC	CDCA5 →	+0.717	+1.818	<.001	<.001	3	3
LUAD	USP9YP5 →	+0.045	+5.748	<.001	.001	3	3
BLCA	MTA2 →	+0.604	+3.222	<.001	.009	3	3
UCEC	FADS1 →	+0.670	+2.050	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

NCAPG by DDX20 expression — UCEC

Explore this box plot interactively →