DDX20

Across TCGA cell cohorts, DDX20 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,757 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DDX20-associated GO terms across cancer lineages are Telomeric 3' overhang formation, DNA replication checkpoint signaling, and Protection from non-homologous end joining at telomere. Each is linked with DDX20 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX20-to-partner and partner-to-DDX20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomeric 3' overhang formation grouped by DDX20-low versus DDX20-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX20→partner) and Y-score (partner→DDX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Telomeric 3' overhang formation →	+0.161	+0.911	<.001	<.001	3	19
BONE	DNA replication checkpoint signaling →	+0.164	+0.712	.007	.001	3	19
OVARY	Protection from non-homologous end joining at telomere →	+0.118	+0.701	<.001	<.001	3	17
SOFT_TISSUE	Mitotic DNA replication checkpoint signaling →	+0.151	+0.671	<.001	<.001	3	17
BONE	Double-strand break repair via break-induced replication →	+0.235	+0.901	<.001	<.001	3	17
BONE	Positive regulation of mRNA splicing, via spliceosome →	+0.153	+0.873	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,757 associations by consensus.

Telomeric 3' overhang formation by DDX20 expression — BREAST

Explore this box plot interactively →