DDX19B

Across TCGA cell cohorts, DDX19B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DDX19B-associated genes across cancer lineages are RAX2, OR2AJ1, and OR2C1. Each is linked with DDX19B in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX19B-to-partner and partner-to-DDX19B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAX2 grouped by DDX19B-low versus DDX19B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX19B→partner) and Y-score (partner→DDX19B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RAX2 →	+0.089	+4.196	<.001	.002	3	1
LARGE_INTESTINE	OR2AJ1 →	+0.015	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR2C1 →	+0.119	+3.725	.001	.008	2	1
LARGE_INTESTINE	PCDH11X →	+0.104	+3.877	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

RAX2 by DDX19B expression — LARGE_INTESTINE

Explore this box plot interactively →