DDX12P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DDX12P Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDX12P data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher DDX12P Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated DDX12P expression acts as an unfavorable survival marker.

LIHC, COAD, and SKCM are the cancer types where DDX12P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSMedianAll0.1060.555.00612view →
COADDFSMedianAll0.4360.793.0097view →
SKCMDFSMedianIII,IV0.0880.613.0186view →
KIRCOSMedianAll0.5230.875.0194view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration