DDX12P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDX12P mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDX12P-associated genes across cancer lineages are MEK1, FOXO3a_pS318_S321, and NDRG1_pT346. Each is linked with DDX12P in more than 1 cancer types. Because this analysis shows association rather than direction, both DDX12P-to-partner and partner-to-DDX12P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX12P→partner) and Y-score (partner→DDX12P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.539+3.000.010.03732
UCECFOXO3a_pS318_S321 →-0.181-3.000.012.03731
UCECNDRG1_pT346 →-0.599-3.000.034.03731
UCECTuberin →+0.475+3.000.002.03731
UCECYB-1_pS102 →-0.248-3.000.020.03731
UCECeIF4E →+0.263+3.000.031.03721
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

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