DDX11L8

Across TCGA patient cohorts, DDX11L8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,734 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DDX11L8-associated GO terms across cancer lineages are Peptidyl-lysine modification, Obsolete regulation of histone modification, and Negative regulation of gene expression, epigenetic. Each is linked with DDX11L8 in more than 18 cancer types. Because this analysis shows association rather than direction, both DDX11L8-to-partner and partner-to-DDX11L8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by DDX11L8-low versus DDX11L8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11L8→partner) and Y-score (partner→DDX11L8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine modification →	+0.046	+0.137	<.001	<.001	3	19
STAD	Obsolete regulation of histone modification →	+0.062	+0.275	<.001	<.001	3	19
STAD	Negative regulation of gene expression, epigenetic →	+0.069	+0.288	<.001	<.001	3	19
STAD	Macromolecule methylation →	+0.064	+0.246	<.001	<.001	3	19
DLBC	Positive regulation of DNA metabolic process →	+0.056	+0.148	.001	.002	2	19
STAD	tRNA metabolic process →	+0.070	+0.250	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,734 associations by consensus.

Peptidyl-lysine modification by DDX11L8 expression — STAD

Explore this box plot interactively →