DDX11L5

Across TCGA patient cohorts, DDX11L5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,113 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DDX11L5-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of DNA repair, and mRNA export from nucleus. Each is linked with DDX11L5 in more than 11 cancer types. Because this analysis shows association rather than direction, both DDX11L5-to-partner and partner-to-DDX11L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by DDX11L5-low versus DDX11L5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11L5→partner) and Y-score (partner→DDX11L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.047	+0.038	<.001	<.001	3	12
STAD	Positive regulation of DNA repair →	+0.043	+0.042	<.001	<.001	3	11
STAD	mRNA export from nucleus →	+0.048	+0.050	<.001	.001	2	11
STAD	DNA strand elongation →	+0.048	+0.044	<.001	.003	2	11
STAD	Regulation of double-strand break repair →	+0.044	+0.046	<.001	<.001	3	10
STAD	Telomere organization →	+0.044	+0.047	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,113 associations by consensus.

Regulation of DNA repair by DDX11L5 expression — STAD

Explore this box plot interactively →