DDX11L17

Across TCGA patient cohorts, DDX11L17 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,928 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DDX11L17-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Positive regulation of DNA repair, and tRNA metabolic process. Each is linked with DDX11L17 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDX11L17-to-partner and partner-to-DDX11L17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by DDX11L17-low versus DDX11L17-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11L17→partner) and Y-score (partner→DDX11L17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	DNA-templated DNA replication maintenance of fidelity →	+0.035	+0.491	<.001	<.001	3	8
TGCT	Positive regulation of DNA repair →	+0.025	+0.492	<.001	<.001	3	8
TGCT	tRNA metabolic process →	+0.020	+0.411	<.001	<.001	3	7
TGCT	tRNA processing →	+0.024	+0.598	<.001	<.001	3	7
TGCT	RNA polymerase II preinitiation complex assembly →	+0.024	+0.567	<.001	<.001	3	7
LAML	Regulation of telomerase activity →	+0.028	+0.450	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,928 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by DDX11L17 expression — TGCT

Explore this box plot interactively →