DDX11-AS1

Across TCGA pan-cancer cohorts, DDX11-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated DDX11-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher DDX11-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DDX11-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and HNSC show a favorable association.

LIHC, ACC, and MESO are the cancer types where DDX11-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.696	0.848	<.001	123	view →
ACC	DFS	Median	All	0.333	0.813	<.001	122	view →
MESO	OS	Median	All	0.271	0.497	<.001	97	view →
KIRC	DFS	Median	All	0.757	0.845	<.001	95	view →
KICH	DFS	Median	III,IV	0.355	1.000	.001	91	view →
UVM	DFS	Median	All	0.742	0.411	.006	41	view →
COAD	DFS	Tertile	IV	0.361	0.749	.007	36	view →
SARC	DFS	Quartile	All	0.511	0.716	<.001	26	view →
HNSC	DFS	Median	IV	0.721	0.562	.003	20	view →
OV	DFS	Quartile	III,IV	0.578	0.435	.013	18	view →
PRAD	DFS	Quartile	All	0.886	0.977	<.001	18	view →
LUAD	OS	Quartile	All	0.757	0.861	.012	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

DDX11-AS1–LIHC (OS)

Open the LIHC breakdown →