DDX11-AS1

Across TCGA pan-cancer cohorts, DDX11-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DDX11-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DDX11-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DDX11-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, LUAD, and BLCA are the cancer types where DDX11-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DDX11-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.410	<.001	12	view →
LUAD	All	IV	+1.214	<.001	11	view →
BLCA	Male	All	+0.945	<.001	11	view →
KIRP	All	IV	+0.802	<.001	11	view →
HNSC	Male	III,IV	+0.690	<.001	11	view →
LIHC	Female	II,III,IV	+0.430	<.001	9	view →
UCEC	All	III,IV	+1.105	<.001	8	view →
STAD	All	II,III,IV	+0.671	<.001	8	view →
COAD	Female	II,III,IV	+0.548	<.001	8	view →
LUSC	Female	All	+1.196	<.001	7	view →
BRCA	All	III,IV	+0.441	<.001	6	view →
ESCA	All	All	+0.527	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DDX11-AS1–KIRC

Open the KIRC breakdown →