DDT

Across TCGA cell cohorts, DDT protein abundance is significantly associated with the RNA expression of many other genes, with 3,294 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DDT-associated genes across cancer lineages are CHCHD10, TXN2, and TGFB1. Each is linked with DDT in more than 7 cancer types. Because this analysis shows association rather than direction, both DDT-to-partner and partner-to-DDT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDT versus CHCHD10 in STOMACH, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDT→partner) and Y-score (partner→DDT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CHCHD10 →	+1.485	+2.128	.008	<.001	3	8
STOMACH	TXN2 →	+1.034	+1.954	.002	.001	3	7
BREAST	TGFB1 →	-2.822	-1.064	<.001	.002	3	6
OVARY	SNRPD3 →	+0.972	+1.645	<.001	<.001	3	6
OVARY	ANKRD54 →	+0.555	+1.014	.003	.004	3	6
URINARY_TRACT	NGLY1 →	+0.976	+3.175	.008	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

DDT vs CHCHD10 — STOMACH

Explore this scatter interactively →