DDR2

Across TCGA patient cohorts, DDR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,107 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDR2-associated proteins across cancer lineages are MSRB3, MYLK, and CNN2. Each is linked with DDR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DDR2-to-partner and partner-to-DDR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDR2 versus MSRB3 in UCEC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDR2→partner) and Y-score (partner→DDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSRB3 →	+0.918	+1.077	<.001	<.001	3	10
COAD	MYLK →	+0.927	+0.999	<.001	<.001	3	10
BRCA	CNN2 →	+0.745	+1.076	<.001	<.001	3	10
OV	COPZ2 →	+0.773	+1.285	<.001	<.001	3	10
OV	FLNA →	+0.620	+1.766	<.001	<.001	3	10
COAD	FLNA_S2152 →	+0.722	+1.330	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,107 associations by consensus.

DDR2 vs MSRB3 — UCEC

Explore this scatter interactively →