DDOST

Across TCGA patient cohorts, DDOST RNA expression is significantly associated with the protein abundance of many other proteins, with 10,117 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDOST-associated proteins across cancer lineages are KIAA2013, UBE4B, and KIAA0319L. Each is linked with DDOST in more than 4 cancer types. Because this analysis shows association rather than direction, both DDOST-to-partner and partner-to-DDOST results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDOST versus KIAA2013 in PDAC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDOST→partner) and Y-score (partner→DDOST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KIAA2013 →	+0.300	+0.238	.004	.004	3	5
OV	UBE4B →	+0.306	+0.676	<.001	<.001	3	5
LSCC	KIAA0319L →	+0.343	+0.457	<.001	<.001	3	5
COAD	NUDC_T145 →	+0.831	+0.405	.003	.006	3	4
LUAD	PRRC2A →	+0.239	+0.375	<.001	<.001	3	4
PDAC	PURA →	-0.220	-0.322	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,117 associations by consensus.

DDOST vs KIAA2013 — PDAC

Explore this scatter interactively →