DDIT3

Across TCGA patient cohorts, DDIT3 RNA expression is significantly associated with the RNA expression of many other genes, with 16,950 significant associations in total. UVM shows the largest number of these associations.

The most reproducible DDIT3-associated genes across cancer lineages are ZFAND2A, MIR616, and IFRD1. Each is linked with DDIT3 in more than 29 cancer types. Because this analysis shows association rather than direction, both DDIT3-to-partner and partner-to-DDIT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDIT3 versus ZFAND2A in ESCA, with a Pearson correlation of 0.46.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIT3→partner) and Y-score (partner→DDIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	ZFAND2A →	+1.027	+0.884	<.001	<.001	3	30
ACC	MIR616 →	+1.246	+0.938	<.001	<.001	3	29
UVM	IFRD1 →	+1.543	+1.258	<.001	<.001	3	29
UVM	CNPY2 →	+0.646	+1.311	<.001	<.001	3	28
KICH	TRIB3 →	+2.149	+1.113	<.001	<.001	3	28
KICH	ATF4 →	+0.809	+1.259	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,950 associations by consensus.

DDIT3 vs ZFAND2A — ESCA

Explore this scatter interactively →