DDIAS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DDIAS RNA expression is significantly associated with the protein abundance of many other proteins, with 24,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DDIAS-associated proteins across cancer lineages are RPL12_S38, RRM2, and SMC2. Each is linked with DDIAS in more than 9 cancer types. Because this analysis shows association rather than direction, both DDIAS-to-partner and partner-to-DDIAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDIAS versus RPL12_S38 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDIAS→partner) and Y-score (partner→DDIAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRPL12_S38 →+1.252+0.971<.001<.001310
LUADRRM2 →+0.901+0.893<.001<.001310
GBMSMC2 →+0.717+0.855<.001<.001310
GBMSMC4 →+0.702+0.847<.001<.001310
LUADKPNA2 →+0.687+0.915<.001<.001310
LUADMKI67_S2528 →+1.405+0.833<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 24,704 associations by consensus.

DDIAS vs RPL12_S38 — OV

Per-sample scatter of DDIAS vs RPL12_S38 in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration