DDHD2

Across TCGA patient cohorts, DDHD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,292 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDHD2-associated proteins across cancer lineages are NSD3, PLPBP, and ASH2L. Each is linked with DDHD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDHD2-to-partner and partner-to-DDHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDHD2 versus NSD3 in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDHD2→partner) and Y-score (partner→DDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NSD3 →	+0.707	+1.026	<.001	<.001	3	8
BRCA	PLPBP →	+0.451	+0.772	<.001	<.001	3	8
LSCC	ASH2L →	+0.468	+0.887	<.001	<.001	3	7
LSCC	BAG4 →	+0.655	+0.877	<.001	<.001	3	7
LSCC	ERLIN2 →	+0.670	+0.765	<.001	<.001	3	7
HNSC	CASP4 →	-0.521	-0.752	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,292 associations by consensus.

DDHD2 vs NSD3 — LSCC

Explore this scatter interactively →