DDHD2

Across TCGA patient cohorts, DDHD2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,105 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDHD2-associated genes across cancer lineages are FGFR1, BAG4, and TM2D2. Each is linked with DDHD2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDHD2-to-partner and partner-to-DDHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDHD2 versus FGFR1 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDHD2→partner) and Y-score (partner→DDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FGFR1 →	+1.207	+0.537	<.001	<.001	3	8
LSCC	BAG4 →	+1.021	+0.522	<.001	<.001	3	7
HNSC	TM2D2 →	+0.915	+0.347	<.001	<.001	3	7
LSCC	ASH2L →	+1.001	+0.587	<.001	<.001	3	6
LSCC	PLPBP →	+0.800	+0.533	<.001	<.001	3	6
LSCC	ERLIN2 →	+0.893	+0.520	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,105 associations by consensus.

DDHD2 vs FGFR1 — BRCA

Explore this scatter interactively →